- 01 Introduction
- 02 Biology of DNA
- 03 Practical Issues Specific to DNA Evidence
- 04 Introduction to the Forensic DNA Laboratory
- 05 Assuring Quality in DNA Testing
- 06 Understanding a Forensic DNA Lab Report
- 07 Statistics and Population Genetics
- 08 Mitochondrial DNA & Y-STR Analysis
- 09 Forensic DNA Databases
- 10 Collection of DNA Evidence from Suspects and Arrestees
- 11 Pretrial DNA Evidence Issues
- 12 Victim Issues
- 13 Trial Presentation
- 14 Postconviction DNA Cases
- 15 Emerging Trends
Principles of Forensic DNA
for Officers of the Court
for Officers of the Court
Module 4 :: Intro To the Lab
Topic 1 :: History and Development of Forensic DNA Analysis
DNA Typing—DQα (DQA1)/ Polymarker
The first forensic application of PCR used the HLA DQ-alpha (DQA1) system which was expanded to include additional genetic systems called Polymarker™ (PM).
Although DQa/Polymarker was faster and more sensitive than RFLP, results were less discriminating. For example, matching profiles might be found in one in several thousand people. In RLFP, the match could be one in several million.
